Pharmaceutical industry has refrained from participating in social media forums due to a lack of clarity on what they can do while still remaining compliant with existing FDA guidelines. We believe that like all other industries, pharmaceutical industry should also listen to social media for numerous benefits that it can derive across the pharmaceutical value chain—drug development, procurement, sales & marketing and post market launch etc. This document focuses on how the pharmaceutical industry can benefit from listening to patients’ sentiments on social media and derive insights across its brand, off label use, side effects, patient needs etc.