Remote Patient Monitoring (RPM) is a branch of telehealth where subjects/patients are monitored remotely outside the four walls of a typical clinic setting, by leveraging increased penetration of mobility and the advancements in IoT technologies (wearables, biosensors, connected devices) and data management techniques. The volume of data generated from these sources will supplement the insights derived for a particular disease/condition. This is becauase analyzing and correlating this continuous stream of real-world data (RWD) with existing data sources have helped researchers identify changes/perturbations in parameters before the onset of clinical syndromes. This has proved to be of significant value in clinical management and course of therapy for certain conditions. Not only this, RPM is seen as an important element in the design of 'Patient Centric Virtual/Siteless Trials’, where the patient/subject's adherence to medication and health outcomes (vitals and other data collected directly from digital devices) are monitored and managed remotely, thus also improving on trial retention and drop-out rates. This has also helped in incorporating real-time data and patient experiences for improvising on trial designs.

The technology stack enabling RPM comprises continuous real-time data collection via wearables or implantable chips to remotely capture, transmit, and store data in a secure centralized platform, which can then be sent to the sponsor, to be loaded in CDMS or EMR as per the extraction protocol.